Malvern Panalytical Analytical Solutions for Manufacturing Productivity

Malvern Instruments

Malvern Panalytical provides a wide range of material characterisation systems used throughout the chemicals and chemical processing industries.

Our cutting-edge systems facilitate the precise measurement of an extensive list of parameters depending on customers’ individual needs, including particle size, shape, rheological properties and elemental concentration, allowing users to optimise their products and better predict how they will behave during use.

Chemical data collection and analysis

Malvern Panalytical helps to solve complex analytical challenges and provide data for optimising products and processes, predicting how products will behave in use and improving productivity. They are used for materials ranging from polymers in solution, particle and nanoparticle suspensions and emulsions, through to sprays and aerosols, industrial bulk powders and high-concentration slurries.

The parameters they measure include:

  • Particle shape, size and concentration, and zeta potential
  • Protein charge
  • Molecular weight, mass, conformation, interactions and stability
  • Rheological properties
  • Chemical identification

Laser diffraction for measuring particle size and size distributions

Laser diffraction is a widely used particle sizing technique for materials from sub-micron to several millimetres in size.

Mastersizer 3000 is a laboratory instrument that delivers rapid, accurate particle size distributions for wet and dry dispersions. It offers exceptional performance in a small footprint and delivers highly reliable, operator-independent measurements.

Insitec systems provide online continuous particle size analysis for efficient, cost-effective monitoring and control of industrial processes. They are suitable for process streams from dry powders to hot, sticky slurries, sprays and emulsions.

Spraytec measures spray particle and droplet size distributions in real-time during the course of a spray event, providing data for efficient development of sprays and aerosols. Flexible configuration enables droplet size measurement for a wide range of products.

Dynamic light scattering for characterising submicron particle dispersions

Dynamic light scattering (DLS) is a non-invasive, well-established technique for measuring the size and size distribution of molecules and particles in the submicron region, with the latest technology measuring less than 1nm. It is typically used to characterise particles, emulsions or molecules dispersed or dissolved in a liquid.

The Zetasizer series measures from less than 1nm to several microns using DLS. Zetasizer Nano systems also measure zeta potential and electrophoretic mobility using electrophoretic light scattering, and molecular weight using static light scattering.

Nanoparticle tracking analysis to visualise and measure nanoparticles

Malvern Panalytical’s NanoSight systems use nanoparticle tracking analysis (NTA) to characterise nanoparticles from 10nm to 2,000nm in solution. Each particle is individually but simultaneously analysed by direct observation and measurement of diffusion events.

This particle-by-particle methodology produces high-resolution results for particle size distribution and concentration, with visual validation. A fluorescence mode provides differentiation of labelled or naturally fluorescing particles.

Particle shape and chemical identification

Particle shape and size can significantly impact the performance and process handling of particulate materials.

It may influence properties such as the bioavailability of drug particles in tablets and suspensions, material strength in metal and ceramic sintered components, printing quality of toners and solder pastes, packing behaviour of chromatography columns, quality of mineral-based coatings finishes and the cutting performance of silicon carbide (SiC) abrasives for solar panel manufacture.

Morphologi imaging-based systems provide particle size and shape measurement for dispersed samples from 0.5 microns to several millimetres.

The addition of Raman spectroscopy in the Morphologi G4-ID system combines automated imaging with chemical identification of individual particles in a technique known as morphologically directed Raman spectroscopy (MDRS).This enables possible chemical identification of individual particles within a multi-component blend.

Triple detection GPC to identify polymer molecular weight, size and structure

Also known as size exclusion chromatography (SEC), gel permeation chromatography (GPC) first separates dissolved macromolecules by size, based on their elution from a gel-filled chromatography column.

Light scattering, viscometer and concentration detectors then measure absolute molecular weight, molecular size and intrinsic viscosity, providing information on macromolecular structure, conformation, aggregation and branching.

These parameters are fundamental to polymer performance in multiple applications. Information from Malvern Panalytical’s GPC / SEC systems helps in controlling the strength, toughness and other performance attributes of materials and tailoring the behaviour of polymer-based products.

Measurement of rheological properties

Rotational, capillary and microfluidic flow rheometers from Malvern Panalytical enable measurement of flow and deformation properties of materials, from dilute, weakly structured solutions to concentrated gels, slurries and pastes. The resulting data is used to understand and control product stability and performance.

Rosand capillary rheometers characterise the rheology of materials by extrusion under the high pressures, shear rates and temperatures relevant to processing. Materials include polymer melts, ceramics, foodstuffs, inks and coatings.

About Malvern Panalytical

Malvern Panalytical was formally established on 1 January 2017 by the merger of UK company Malvern Instruments and Netherlands-based PANalytical, along with its subsidiaries ASD and Claisse.

The company has a global sales and service presence and currently employs more than 2,000 staff worldwide, while operating a number of research and manufacturing sites across Europe, the US and China.

Malvern Panalytical is dedicated to the development of innovative materials characterisation tools for a wide variety of industrial applications in order to deliver valuable actionable insight and assist in the creation of high-quality products.

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Press Release

Upcoming Webinars by Malvern Panalytical

A list of live webinars that Malvern Panalytical will be hosting over the next few months.

White Papers

Battery Research and Quality Control Solutions

Empower your research and production with advanced analytical solutions.

Malvern Instruments Ltd.

Enigma Business Park

Grovewood Road


WR14 1XZ


United Kingdom

+44 1684 892456 +44 1684 892789 Malvern Store

Malvern Panalytical Images

Products and Services

Mastersizer Range: Particle Size Analysers.

The Mastersizer range comprises easy-to-use, accurate and reliable particle size analysers. The high-performance devices cover particle sizes ranging from nanometers to millimetres, providing reliable independent measurements.

Manual MicroCal PEAQ-DSC: Easy-to-use Microcalorimetry

MicroCal PEAQ-DSC systems deliver highly sensitive, easy-to-use microcalorimetry that reduce the time and cost associated with stability testing and comparability analysis.

MicroCal PEAQ-DSC Microcalorimeters Product Range

MicroCal PEAQ-DSC microcalorimeters are effective and easy-to-use tools that facilitate thermal stability characterisation of proteins and other biomolecules, primarily for biopharmaceutical development and manufacturing applications.

m-VROCi for High-resolution Viscosity Measurements

The Malvern m-VROCi utilizes unique microfluidic viscometer / rheometer on a chip technology to provide high-resolution viscosity measurements into the ultra-high shear rate regime.

Automated MicroCal PEAQ-DSC for Protein Stability Analysis

MicroCal PEAQ-DSC automated systems provide sensitive, high throughput protein stability analysis with low sample consumption in an automated, fully integrated platform to facilitate maximum productivity.

Viscosizer TD: Automated Biophysical Characterisation Tool

Malvern Viscosizer TD is an automated biophysical characterisation tool utilising Taylor Dispersion Analytics and providing ultra-low volume, solution-based molecular size and stability measurement capabilities, combined with Poiseuille flow for relative viscosity assessment.

Zetasizer Range for Particle and Molecule Measurement

The Malvern Zetasizer series measures particle and molecule size from below a nanometer to several microns using dynamic light scattering, zeta potential and electrophoretic mobility using electrophoretic light scattering, and molecular weight using static light scattering.

Zetasizer AT: Nanoparticle Characterisation System

Malvern's Zetasizer AT brings the industry leading Dynamic Light Scattering (DLS) technology of the Zetasizer Nano to the process development and manufacturing arena, enabling real-time monitoring of nanoscale particle processes online.

White Papers

Battery Research and Quality Control Solutions

Empower your research and production with advanced analytical solutions.

27th March 2020

Characterisation of Liposomes Using Complementary Techniques

Liposomes have been attractive delivery systems for decades due to their composition of natural biological lipids and structural resemblance to cell membranes suggesting metabolic compatibility, low toxicity, overall expectations of biocompatibility and lack of a strong immune response.

30th October 2019

Integrating PANalytical system in a 21 CFR Part 11 Compliant Laboratory

The purpose of this document is to describe how PANalytical systems support system owners meeting the requirements of the 21 CFR Part 11 regulations issued by the United States’ FDA.

23rd October 2019

Optimising Metal Powders for Application in Additive Manufacturing

Additive manufacturing (AM) processes have undergone a significant transition in recent years from a simple prototyping solution into an innovative, economically expedient method of component production.

8th August 2019

Studying the Applications and Characterisation of Gold Nanoparticles by Nanoparticle Tracking Analysis

Gold nanoparticles are one of the most popular and extensively researched types of nanoparticle; a Google Scholar search of the term results in over 500,000 hits.

20th May 2019

A Basic Introduction to Rheology

Rheology is as much about the deformation of solid-like materials.

10th May 2019

Achieving High-Performance Light Scattering Analysis with Zetasizer Pro and Zetasizer Ultra

Malvern Panalytical is pleased to offer its latest light scattering analysis systems, Zetasizer Pro and Zetasizer Ultra, which are equipped with both dynamic light scattering (DLS) and electrophoretic light scattering (ELS) capabilities for maximum performance and versatility.

2nd May 2019

Introducing the Principles of X-Ray Fluorescence (XRF) Spectrometry

X-Ray Fluorescence (XRF) spectrometry can be used to identify the chemical composition of an extensive range of materials, including solids, powders and liquids.

6th August 2018

Detecting Trace Polymorphs with Powder X-Ray Diffraction (PXRD)

Powder X-ray diffraction (PXRD) processes are commonly used within the chemicals industry to detect traces of polymorphs.

30th July 2018

Related Projects

Press Release

12th August 2020

A list of live webinars that Malvern Panalytical will be hosting over the next few months.

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14th May 2020

Here is a short update to let you know what Malvern Panalytical is doing to help its customers and ensure that business continues as normally as possible during the Covid-19 pandemic.

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1st April 2020

Malvern Panalytical will be hosting or attending a number of events in the upcoming months.

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31st March 2020

Malvern Panalytical and Concept Life Sciences combine experience and know-how in a unique partnership.

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23rd October 2019

Dolomite Microfluidics is a brand of Blacktrace Holdings Ltd, a company which develops and manufactures groundbreaking technologies for applications in biology, chemistry, microfluidics and nanomaterials.

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4th October 2019

ASTM International, one of the world’s leading standards developers, announced that it will hold its board meeting and related events in Boston, Massachusetts, US, on 13-16 October.

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8th August 2019

Pharmaceutical and chemicals companies have to demonstrate that the drug products they are developing are reproducibly effective and efficient, meeting their desired Quality Target Product Profile (QTPP).

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2nd July 2019

New Model in Technology and Engineering (NMiTE) has announced three appointments to its Board of Trustees, Martin Hitchin, Rowena Innocent and Richard Lindsay-Davies, which will come into effect on 1 July 2019.

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2nd May 2019

Malvern Panalytical has announced the launch of the next-generation of Epsilon 1 X-ray fluorescence (XRF) spectrometers.

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4th September 2018

The invention allows for more rapid and accurate characterization of ore materials compared to other systems of measurement.

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13th August 2018

Lipsomes are often used as drug delivery systems, and therefore it is important that they are well characterised to ensure easy manufacturing and batch release.

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8th August 2018

During virus development processes, it is vital to discern the virus concentration at each stage of the procedure in order to ensure optimise the clone used and facilitate maximum production yields.

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6th August 2018

Malvern Panalytical’s sophisticated Epsilon 4 X-ray fluorescence (XRF) spectrometer is capable of accurately analysing both major and minor elements within cement samples.

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1st August 2018

Originally developed for use with Malvern Panalytical’s innovative X-ray fluorescence (XRF) spectrometry systems, Omnian is also available for the company’s cutting-edge bench-top Epsilon 4 solutions.

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30th July 2018

Leading chemical analysis specialist Malvern Panalytical has announced three major seminar sessions to be held throughout the remainder of 2018.

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27th July 2018

Malvern Panalytical has announced three new exclusive webinar sessions, which are set to be held during August 2018.

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6th July 2018

Material characterisation solutions specialist Malvern Panalytical will be holding a series of webinar sessions throughout this month, which are set to cover a wide range of topics.

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3rd July 2018

Industrial analytical technology specialist Malvern Panalytical is slated to unveil its latest Empyrean multipurpose X-ray diffraction system at the 16th edition of the European Powder Diffraction Conference (EPDIC16), which is set to be held in Edinburgh, UK, from 1-4 July.

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13th June 2018

Malvern Panalytical has unveiled a lineup of exclusive seminar sessions, which are scheduled to take place throughout the remainder of 2018.

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6th June 2018

Malvern Panalytical is pleased to announce that the company will be holding three webinar sessions over the coming months.

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23rd May 2018

Leading measurement and characterisation systems provider Malvern Panalytical has unveiled a new line of Zetasizer® Pro and Ultra units, which have been optimised for the chemicals sector.

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3rd May 2018

UK-based characterisation technology specialist Malvern Panalytical is set to present a series of webinars during May 2018, which will cover a wide range of topics related to the chemicals sector.

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13th April 2018

Material characterisation solutions specialist Malvern Panalytical is pleased to announce that the company will be running a series of webinar sessions during April 2018.

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14th February 2018

Malvern Panalytical is pleased to announce the launch of its new range of Morphologi® particle characterisation systems, Morphologi 4 and Morphologi 4-ID.

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30th January 2018

Malvern Panalytical is pleased to announce the launch of the new Epsilon 4 benchtop analytical tool, which delivers fast and reliable at-line elemental analysis for chemical applications.

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25th January 2018

Dynamic Light Scattering (DLS), alternatively known as either Photon Correlation Spectroscopy or Quasi-Elastic Light Scattering, is an innovative method of analysing the size of small particles within a solution at the sub-micron level.

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19th January 2018

PANalytical is pleased to announce that the first of the company's 2018 series of webinars will take place on 22 February, focussing on the application study of precision agriculture and spectral signatures.

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12th January 2018

Malvern is pleased to announce that the company will be demonstrating its innovative new nanoparticle characterisation platform known as NanoSight NS300 at a live launch event, which is set to take place on 18 January.

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4th December 2017

Malvern Panalytical has announced the launch of a collaborative project that aims to support the development of existing and next generation biopharmaceutical products.

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3rd September 2017

Malvern is pleased to announce that the company will be conducting a webinar entitled 'Transforming the Future of Particle Characterisation: Clarity by Design' on 4 October.

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31st August 2017

Malvern PANalytical is pleased to announce it will be hosting a webinar entitled 'Rheology of Soft Matter: Gels and Soft Glass Transition' on 14 September.

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17th July 2017

Leading analytical X-ray instrumentation and software provider PANalytical is pleased to unveil its latest solution, the new Epsilon 1 X-ray fluorescence (XRF) spectrometer.

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10th July 2017

Understanding the make-up of crystalline structures is a vital aspect of the characterisation of new compounds, and can be regarded as an important first step towards the possibility of tailoring its properties.

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3rd July 2017

Malvern is set to host a series of webinar sessions throughout July and August.

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7th June 2017

Malvern is pleased to announce it will be hosting a number of webinar sessions throughout June, discussing the merits and applications of number of chemical particle analysis methods.

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25th April 2017

Comparative analytical data is at the foundation of any successful biosimilarity programme.

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6th April 2017

As its name implies, a viscometer is used to measure the viscosity of a given fluid.

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7th March 2017

Malvern Instruments will be running two webinar sessions this month; the first will discuss the potential applications of differential scanning calorimetry in protein characterisation, while the second will cover the use of particle size analysis in cement plant operations.

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20th February 2017

On 21 February, Malvern will host the unveiling of the next major step forward in protein stability characterisation for the regulated environment: the new MicroCal PEAQ-DSC.

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19th February 2017

The efficiency of a particular powder bed additive manufacturing process, and the overall quality of the finished components, is to a large extent dependent on the packing density and flow behaviour of the metal powders involved.

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11th December 2016

To celebrate the knowledge, support and dedication of our employees we are introducing our first live panel discussion to help you solve your current challenges. We invite you to write in your questions, comments, feedback and wish lists for our panel to answer.

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4th December 2016

Gel Permeation Chromatography (GPC), also known as Size Exclusion Chromatography (SEC), is a very popular analytical tool for characterizing natural and synthetic polymers.

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8th November 2016

The market for batteries is rapidly growing, and the increased demand for portable electronic devices, including mobile phones and laptops requires greater advances in battery technology in order to provide a lightweight, long-lasting and stable power source.

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7th November 2016

The self-association characteristics of molecules in dilute solutions can provide an assessment of stability at an early stage in development.

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2nd November 2016

Paints or coatings, similar to many commercial products, must be optimized for their end use performance, which for paints and coatings includes leveling behavior, pigment dispersability, sag resistance, applicator loading and film thickness, all of which depend on a coatings rheological behavior.

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10th October 2016

Malvern has announced it will be demonstrating its new nanoparticle size and concentration measurer NanoSight NS3000, which uses Nanoparticle Tracking Analysis (NTA).

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7th September 2016

Malvern is to host a webinar about zeta potential and its importance when controlling formulation stability and product performance.

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18th August 2016

In recent news, the FDA has used key data generated on the Malvern Morphologi G3-ID system to approve the first generic nasal spray drug product containing mometasone furoate. The primary challenge with this approval was proving bioequivalence compared to the innovator product.

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7th June 2016

Malvern Instruments has launched the new Zetasizer AT, a robust, online, automated analyzer that uses dynamic light scattering (DLS) to automatically measure the size of nanoparticles in suspensions and emulsions.

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4th March 2016

Researchers working on the European Metrology Research Project NanoChOp (chemical and optical characterization of nanomaterials in biological systems), funded by EURAMET, have concluded that the NanoSight Nanoparticle tracking analysis system from Malvern Instruments offers unique insight into the behavior of nanoparticles in biological systems.

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14th December 2015

The latest software release along with an expansion of the global technical specialist team, highlight Malvern Instruments' ongoing commitment to extending and supporting the application of NanoSight, a nanoparticle characterisation technology with unique capabilities.

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3rd December 2015

A collaboration between UK firm Malvern Instruments and California-based Bio-Rad has developed new analytical tools for the rapid identification of unknown particles.

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2nd November 2015

Insights shared by William Bernt, director of Particle Characterization Laboratories, highlight the transformative impact of adding a Malvern NanoSight Nanoparticle Tracking Analysis (NTA) system to the analytical toolkit for nanoparticles.

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14th October 2015

Malvern's new tools for specific analytical challenges in biopharma development will take centre stage at AAPS Annual Meeting and Exposition 2015, in Orlando, US.

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1st October 2015

Malvern Instruments has established a new biopharmaceutical applications laboratory in the heart of San Diego's biotechnology cluster.

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18th September 2015

Insight from CP Kelco, a global leader in the speciality hydrocolloids market, provides a blueprint for the intelligent, cost-efficient deployment of gel permeation / size exclusion chromatography (GPC/SEC) in biopolymer manufacture.

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18th September 2015

Malvern Instruments has launched a new and improved rSolution platform on their Kinexus rotational rheometer to help customers use rheological measurements more effectively.

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24th February 2015

Analytical systems from Malvern Instruments are now used routinely to advance inkjet formulation at Domino Printing Sciences in the UK, one of the world's leading printing technology companies.

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Regional Offices

Malvern Instruments Ltd.

Enigma Business Park

Grovewood Road


WR14 1XZ


United Kingdom

+44 1684 892456 +44 1684 892789 Malvern Store
Malvern Canada

4995 Levy Street


Quebec H4R 2N9


+1 800 932 0101 +1 508 768 6403
Malvern Instruments China

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Building 13, No 99 Tianzhou Road

Shanghai 200233


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Hyogo Prefecture 650-0047


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United States of America

+1 508 768 6400 +1 508 768 6403 +1 508 768 6401