The EU's European Chemical Agency (ECHA) has reached its first deadline and completed registration of 4,300 chemical substances under its REACH chemicals regulation.
The agreement also registered 900 chemicals not sold in Europe ahead of the regulation becoming a law.
REACH registers chemical substances sold in the EU in volumes greater than 1,000t-per-year and substances of very-high concern.
According to the ECHA, large companies made abut 86% of the registrations, with the remainder made by small or medium-sized firms. Most registrations came from Germany, UK, Netherlands, France and Belgium.
The registration has been designed to promote better health, safety and environmental protection in the EU.