Maximising Absolute Molecular Weight via Synthetic Polymers
Malvern’s OMNISEC system is a completely new multi-detector GPC system that combines light scattering, refractive index (RI), ultraviolet (UV) and intrinsic viscosity (IV) detectors to generate a large amount of information about a sample simultaneously. Its new design means it is capable of making these measurements with less sample and lower molecular weights than ever before.
GPC/SEC (gel-permeation or size-exclusion chromatography) is the most commonly used tool for assessing these parameters. The principle of GPC involves separating the sample as it travels through a porous but inert column matrix. While smaller molecules penetrate the pores more deeply, larger molecules are excluded and thus travel through the column faster. The result is a separation based on hydrodynamic volume. However, in most cases, the desire is to know the molecular weight of the sample.
In this application note, the molecular weight, molecular weight distribution and size of three common polymers are measured using the OMNISEC system.