Malvern Instruments

Analytical Solutions for Manufacturing Productivity

Malvern Instruments

Malvern provides a wide range of material characterisation systems used throughout the chemicals and chemical processing industries.

Chemical data collection and analysis

Malvern helps to solve complex analytical challenges and provide data for optimising products and processes, predicting how products will behave in use and improving productivity. They are used for materials ranging from polymers in solution, particle and nanoparticle suspensions and emulsions, through to sprays and aerosols, industrial bulk powders and high-concentration slurries.

The parameters they measure include:

  • Particle shape, size and concentration, and zeta potential
  • Protein charge
  • Molecular weight, mass, conformation, interactions and stability
  • Rheological properties
  • Chemical identification

Laser diffraction for measuring particle size and size distributions

Laser diffraction is a widely used particle sizing technique for materials from sub-micron to several millimetres in size.

Mastersizer 3000 is a laboratory instrument that delivers rapid, accurate particle size distributions for wet and dry dispersions. It offers exceptional performance in a small footprint and delivers highly reliable, operator-independent measurements.

Insitec systems provide online continuous particle size analysis for efficient, cost-effective monitoring and control of industrial processes. They are suitable for process streams from dry powders to hot, sticky slurries, sprays and emulsions.

Spraytec measures spray particle and droplet size distributions in real-time during the course of a spray event, providing data for efficient development of sprays and aerosols. Flexible configuration enables droplet size measurement for a wide range of products.

Dynamic light scattering for characterising submicron particle dispersions

Dynamic light scattering (DLS) is a non-invasive, well-established technique for measuring the size and size distribution of molecules and particles in the submicron region, with the latest technology measuring less than 1nm. It is typically used to characterise particles, emulsions or molecules dispersed or dissolved in a liquid.

The Zetasizer series measures from less than 1nm to several microns using DLS. Zetasizer Nano systems also measure zeta potential and electrophoretic mobility using electrophoretic light scattering, and molecular weight using static light scattering.

Nanoparticle tracking analysis to visualise and measure nanoparticles

Malvern NanoSight systems use nanoparticle tracking analysis (NTA) to characterise nanoparticles from 10nm to 2,000nm in solution. Each particle is individually but simultaneously analysed by direct observation and measurement of diffusion events.

This particle-by-particle methodology produces high-resolution results for particle size distribution and concentration, with visual validation. A fluorescence mode provides differentiation of labelled or naturally fluorescing particles.

Particle shape and chemical identification

Particle shape and size can significantly impact the performance and process handling of particulate materials.

It may influence properties such as the bioavailability of drug particles in tablets and suspensions, material strength in metal and ceramic sintered components, printing quality of toners and solder pastes, packing behaviour of chromatography columns, quality of mineral-based coatings finishes and the cutting performance of silicon carbide (SiC) abrasives for solar panel manufacture.

Morphologi G3 and Sysmex FPIA-3000 imaging-based systems provide particle size and shape measurement for dispersed samples from 0.5 microns to several millimetres.

The addition of Raman spectroscopy in the Morphologi G3-ID system combines automated imaging with chemical identification of individual particles in a technique known as morphologically directed Raman spectroscopy (MDRS).This enables possible chemical identification of individual particles within a multi-component blend.

Triple detection GPC to identify polymer molecular weight, size and structure

Also known as size exclusion chromatography (SEC), gel permeation chromatography (GPC) first separates dissolved macromolecules by size, based on their elution from a gel-filled chromatography column.

Light scattering, viscometer and concentration detectors then measure absolute molecular weight, molecular size and intrinsic viscosity, providing information on macromolecular structure, conformation, aggregation and branching.

These parameters are fundamental to polymer performance in multiple applications. Information from Malvern's GPC / SEC systems helps in controlling the strength, toughness and other performance attributes of materials and tailoring the behaviour of polymer-based products.

Measurement of rheological properties

Rotational, capillary and microfluidic flow rheometers from Malvern enable measurement of flow and deformation properties of materials, from dilute, weakly structured solutions to concentrated gels, slurries and pastes. The resulting data is used to understand and control product stability and performance.

Kinexus rotational rheometers are sensitive enough to measure the viscosity of dilute polymer solutions, yet sufficiently robust enough to measure viscoelasticity of high modulus polymers or composites. Unique software provides total flexibility of test set-up for research and development, through to standard operating procedure (SOP) driven testing for more routine rheological requirements.

Rosand capillary rheometers characterise the rheology of materials by extrusion under the high pressures, shear rates and temperatures relevant to processing. Materials include polymer melts, ceramics, foodstuffs, inks and coatings.

Contact Details

Malvern Instruments Ltd.
Enigma Business Park
Grovewood Road
WR14 1XZ
United Kingdom
+44 1684 892456
+44 1684 892789
Malvern Store

Available White Papers


Top Ten Factors to Consider When Purchasing a New DLS Instrument 19 June 2017 When investing in a new dynamic light scattering (DLS) instrument, its physical components and technical specifications are obviously important factors to take into account.


Analysing Polymer Degradation using GPC / SEC Methodology 12 June 2017 The effects of processing a polymer has on its molecular weight, molecular weight distribution, and solution viscosity are important for chemical industry manufacturers to understand if they are to fully optimise their operations.


KBI Biopharma on How Malvern Instruments Aided Their Search for a Commercial Advantage 01 June 2017 The KBI Particle Core team needed a tool to help them complete their in-house characterization service by identifying particles they detected in the subvisible and visible size range.


Analysing Fuel Filter Efficiency via Online Laser Diffraction 22 May 2017 The unwanted introduction of water in diesel fuel is one of the most common cited causes of engine breakdown, and therefore its removal is essential for the safe and efficient operation of diesel engines.


Using GPC / SEC Techniques for Compositional Analysis 15 May 2017 As synthetic polymers became more prevalent across the chemicals industry, a desire has arisen to fine-tune the physical properties of these materials in order to optimise the end-products for their intended application.

Company Videos